Research workbench
Cryo-EM structure of enteropathogenic escherichia COLI type III secretion system espa filament
Analyse Cryo-EM structure of enteropathogenic escherichia COLI type III secretion… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7KHW
- Type
- protein
- Length
- 8,700 residues
- Chains
- 50
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Translocon espa
- UniProt
- B7UM94
- Pockets
- 20 · best druggability 0.87
Structure
electron microscopy · 1 distinct chain · 60% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T, U, V, W, X, Y, Z, a, b, c, d, e, f, g, h, i, j, k, l, m, n, o, p, q, r, s, t, u, v, w, x | Translocon espa | protein | 174 | 60% helix, 0% strand | B7UM94 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1127 | 0.87 | 0.88 | 132 | empty |
| 2 | 1056 | 0.87 | 0.88 | 132 | empty |
| 3 | 1142 | 0.87 | 0.88 | 132 | empty |
| 4 | 1057 | 0.86 | 0.87 | 126 | empty |
| 5 | 1030 | 0.86 | 0.87 | 129 | empty |
Interfaces
217 interfaces between chains.
- N–O · 1709 Ų buried · 9 hydrogen bonds · protein-protein
- h–i · 1708 Ų buried · 9 hydrogen bonds · protein-protein
- P–Q · 1706 Ų buried · 9 hydrogen bonds · protein-protein
- r–s · 1705 Ų buried · 9 hydrogen bonds · protein-protein
- E–F · 1705 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 7KHW · Cryo-EM structure of enteropathogenic Escherichia coli type III secretion system EspA… · the same entry in another collection · chain j against j, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7UM94
- Elsewhere: RCSB PDB 7KHW · PDBe 7KHW · UniProt B7UM94
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.