Research workbench
Putative ankyrin repeat domain-containing protein from enterobacter cloacae
Analyse Putative ankyrin repeat domain-containing protein from enterobacter cloacae in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7KB2
- Type
- protein
- Length
- 358 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ANK_REP_REGION domain-containing protein
- UniProt
- A0A0H3CKN4
- Pockets
- 1 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 52% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ANK_REP_REGION domain-containing protein | protein | 179 | 53% helix, 2% strand | A0A0H3CKN4 |
| B | ANK_REP_REGION domain-containing protein | protein | 179 | 51% helix, 2% strand | A0A0H3CKN4 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 2 copies · chains A, B
- 1PE · Pentaethylene glycol · additive · chains A
- ACT · Acetate ion · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 380 | 0.71 | 0.83 | 47 | ACT |
Interfaces
1 interface between chains.
- A–B · 605 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
- 7KB2 · Putative ankyrin repeat domain-containing protein from Enterobacter cloacae · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0H3CKN4
- Elsewhere: RCSB PDB 7KB2 · PDBe 7KB2 · UniProt A0A0H3CKN4
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