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The X-ray crystal structure of SSR4, an S. pombe chromatin remodelling protein: native

Analyse The X-ray crystal structure of SSR4, an S. pombe chromatin remodelling protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7K7W
Type
protein
Length
189 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
SWI/SNF and rsc complexes subunit SSR4
UniProt
Q9P7Y0
Ligands
CL
Pockets
2 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 20% helix, 29% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASWI/SNF and rsc complexes subunit SSR4protein18920% helix, 29% strandQ9P7Y0

Ligands and binding sites

  • CL · Chloride ion · ion · chains A
  • GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12080.600.8123GOL
21050.390.7621empty

Compared structures

  • 7K7W · The X-ray crystal structure of SSR4, an S. pombe chromatin remodelling protein: native · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9P7Y0 · AlphaFold monomer V2.0 prediction for SWI/SNF and rsc complexes subunit SSR4 (Q9P7Y0) · a predicted model of the same protein · chain A against A, TM-score 0.94

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