Research workbench
PIKFYVE/FIG4/VAC14 complex centered on FIG4 - MAP3
Analyse PIKFYVE/FIG4/VAC14 complex centered on FIG4 - MAP3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7K1W
- Type
- protein
- Length
- 462 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- FIG4 sac homology model
- Pockets
- 9 · best druggability 0.72
Structure
electron microscopy · 1 distinct chain · 27% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| F | FIG4 sac homology model | protein | 462 | 27% helix, 29% strand | — |
Pockets
9 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 296 | 0.72 | 0.85 | 42 | empty |
| 2 | 120 | 0.68 | 0.90 | 25 | empty |
| 3 | 55 | 0.66 | 0.94 | 16 | empty |
| 4 | 54 | 0.62 | 0.93 | 20 | empty |
| 5 | 319 | 0.54 | 0.74 | 44 | empty |
Compared structures
- 7K1W · PIKfyve/Fig4/Vac14 complex centered on Fig4 - map3 · the same entry in another collection · chain F against F, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7K1W · PDBe 7K1W
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