Research workbench
Cryo-EM structure of the nonameric escv cytosolic domain from the type III secretion system
Analyse Cryo-EM structure of the nonameric escv cytosolic domain from the type III… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7K08
- Type
- protein
- Length
- 2,988 residues
- Chains
- 9
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Translocator escv
- UniProt
- B7UMA7
- Pockets
- 20 · best druggability 0.74
Structure
electron microscopy · 1 distinct chain · 43% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I | Translocator escv | protein | 332 | 43% helix, 15% strand | B7UMA7 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 896 | 0.74 | 0.78 | 88 | empty |
| 2 | 873 | 0.74 | 0.78 | 90 | empty |
| 3 | 847 | 0.73 | 0.78 | 82 | empty |
| 4 | 345 | 0.71 | 0.83 | 45 | empty |
| 5 | 326 | 0.70 | 0.83 | 50 | empty |
Interfaces
9 interfaces between chains.
- A–B · 963 Ų buried · 22 hydrogen bonds · protein-protein
- D–E · 963 Ų buried · 22 hydrogen bonds · protein-protein
- G–H · 963 Ų buried · 22 hydrogen bonds · protein-protein
- H–I · 962 Ų buried · 22 hydrogen bonds · protein-protein
- C–D · 961 Ų buried · 22 hydrogen bonds · protein-protein
Compared structures
- 7K08 · Cryo-EM structure of the nonameric EscV cytosolic domain from the type III secretion… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B7UMA7
- Elsewhere: RCSB PDB 7K08 · PDBe 7K08 · UniProt B7UMA7
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