Research workbench
Cftr associated ligand (cal) PDZ domain bound to peptidomimetic lycalpmb
Analyse Cftr associated ligand (cal) PDZ domain bound to peptidomimetic lycalpmb in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7JZQ
- Type
- protein
- Length
- 94 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Golgi-associated PDZ and coiled-coil motif-containing protein; Lycalpmb peptide core
- UniProt
- Q9HD26
- Ligands
- VU1
Structure
x-ray diffraction · 2 distinct chains · 19% helix, 39% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Golgi-associated PDZ and coiled-coil motif-containing protein | protein | 87 | 21% helix, 39% strand | Q9HD26 |
| C | Lycalpmb peptide core | protein | 7 | 0% helix, 43% strand | — |
Ligands and binding sites
- VU1 · 4-[(piperidin-1-yl)methyl]benzoic acid · ligand · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–C · 471 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 covalent (covalent ligand).
Compared structures
- 7JZQ · CFTR Associated Ligand (CAL) PDZ domain bound to peptidomimetic LyCALPMB · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HD26 · AlphaFold monomer V2.0 prediction for golgi-associated PDZ and coiled-coil… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HD26
- Elsewhere: RCSB PDB 7JZQ · PDBe 7JZQ · UniProt Q9HD26
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