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BRD2-BD2 in complex with a diacetylated-H2A.Z peptide

Analyse BRD2-BD2 in complex with a diacetylated-H2A.Z peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7JX7
Type: protein
Length: 117 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Bromodomain-containing protein 2; Diacetylated-H2A.Z peptide
UniProt: P25440

Structure

x-ray diffraction · 2 distinct chains · 65% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Bromodomain-containing protein 2	protein	111	68% helix, 0% strand	P25440
B	Diacetylated-H2A.Z peptide	protein	6	0% helix, 0% strand	—

Interfaces

1 interface between chains.

A–B · 448 Å² buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (acetylation).

Compared structures

7JX7 · BRD2-BD2 in complex with a diacetylated-H2A.Z peptide · the same entry in another collection · chain A against A, TM-score 1.00
P25440 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 2 (P25440) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P25440
Elsewhere: RCSB PDB 7JX7 · PDBe 7JX7 · UniProt P25440

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