Research workbench
Stalk of radial spoke 1 attached with doublet microtubule from chlamydomonas reinhardtii
Analyse Stalk of radial spoke 1 attached with doublet microtubule from chlamydomonas… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7JTS
- Type
- protein
- Length
- 1,377 residues
- Chains
- 13
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Radial spoke protein 3; Dynein 8 kda light chain, flagellar outer arm; FAP207; FAP253…
- UniProt
- A8J2J7, Q39580, A0A2K3DJP7, A0A2K3D359, A8IDP6
- Pockets
- 16 · best druggability 0.79
Structure
electron microscopy · 6 distinct chains · 45% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| E | Radial spoke protein 3 | protein | 40 | 45% helix, 15% strand | A8J2J7 |
| F | Radial spoke protein 3 | protein | 48 | 65% helix, 13% strand | A8J2J7 |
| a, b, c, d, e, f, g, h | Dynein 8 kda light chain, flagellar outer arm | protein | 84 | 35% helix, 35% strand | Q39580 |
| m | FAP207 | protein | 184 | 0% helix, 52% strand | A0A2K3DJP7 |
| s | FAP253 | protein | 290 | 67% helix, 5% strand | A0A2K3D359 |
| t | Calmodulin | protein | 143 | 57% helix, 4% strand | A8IDP6 |
Pockets
16 pockets found on a 1 Å grid, 15 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 656 | 0.79 | 0.84 | 89 | empty |
| 2 | 1120 | 0.78 | 0.80 | 164 | empty |
| 3 | 731 | 0.78 | 0.83 | 78 | empty |
| 4 | 744 | 0.77 | 0.82 | 95 | empty |
| 5 | 619 | 0.72 | 0.80 | 68 | empty |
Interfaces
20 interfaces between chains.
- a–s · 707 Ų buried · 4 hydrogen bonds · protein-protein
- a–b · 565 Ų buried · 9 hydrogen bonds · protein-protein
- e–f · 522 Ų buried · 12 hydrogen bonds · protein-protein
- c–d · 498 Ų buried · 7 hydrogen bonds · protein-protein
- s–t · 474 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 7JTS · Stalk of radial spoke 1 attached with doublet microtubule from Chlamydomonas reinhardtii · the same entry in another collection · chain t against t, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A8J2J7
- Every structure of UniProt Q39580
- Every structure of UniProt A0A2K3DJP7
- Every structure of UniProt A0A2K3D359
- Every structure of UniProt A8IDP6
- Elsewhere: RCSB PDB 7JTS · PDBe 7JTS · UniProt A8J2J7 · UniProt Q39580 · UniProt A0A2K3DJP7 · UniProt A0A2K3D359 · UniProt A8IDP6
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