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Crystal structure of a putative nuclease with anti-CAS9 activity from an uncultured clostridia bacterium

Analyse Crystal structure of a putative nuclease with anti-CAS9 activity from an… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7JTA
Type: protein
Length: 112 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: NTF2-like NUCLEASE/ANTI-CRISPR
UniProt: A0A5B9TEE9
Ligands: NO3
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 75% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	NTF2-like NUCLEASE/ANTI-CRISPR	protein	56	0% helix, 75% strand	A0A5B9TEE9

Ligands and binding sites

NO3 · Nitrate ion · ion · 7 copies · chains A, B
MPD · (4S)-2-methyl-2,4-pentanediol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	249	0.49	0.74	48	NO3

Interfaces

1 interface between chains.

A–B · 320 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

7JTA · Crystal structure of a putative nuclease with anti-Cas9 activity from an uncultured… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A5B9TEE9
Elsewhere: RCSB PDB 7JTA · PDBe 7JTA · UniProt A0A5B9TEE9

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