Research workbench
Crystal structure of CFL1-D123S from burkholderia cenocepacia
Analyse Crystal structure of CFL1-D123S from burkholderia cenocepacia in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7JQY
- Type
- protein
- Length
- 2,348 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cif-like 1
- UniProt
- B4EJL9
- Pockets
- 20 · best druggability 0.83
Structure
x-ray diffraction · 3 distinct chains · 45% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, F, G | Cif-like 1 | protein | 293 | 45% helix, 18% strand | B4EJL9 |
| B, D, E, H | Cif-like 1 | protein | 294 | 45% helix, 18% strand | B4EJL9 |
| C | Cif-like 1 | protein | 293 | 46% helix, 17% strand | B4EJL9 |
Pockets
20 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1166 | 0.83 | 0.84 | 120 | empty |
| 2 | 156 | 0.72 | 0.90 | 25 | empty |
| 3 | 165 | 0.70 | 0.88 | 26 | empty |
| 4 | 180 | 0.70 | 0.88 | 30 | empty |
| 5 | 295 | 0.69 | 0.84 | 29 | empty |
Interfaces
11 interfaces between chains.
- C–F · 800 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 655 Ų buried · 6 hydrogen bonds · protein-protein
- C–D · 552 Ų buried · 8 hydrogen bonds · protein-protein
- A–B · 537 Ų buried · 9 hydrogen bonds · protein-protein
- C–H · 503 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 7JQY · Crystal structure of Cfl1-D123S from Burkholderia cenocepacia · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B4EJL9
- Elsewhere: RCSB PDB 7JQY · PDBe 7JQY · UniProt B4EJL9
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