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Adeno-associated virus strain AAV7 capsid icosahedral structure

Analyse Adeno-associated virus strain AAV7 capsid icosahedral structure in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7JOT
Type
protein
Length
518 residues
Chains
1
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Capsid protein
UniProt
Q8JQG0
Pockets
9 · best druggability 0.59

Structure

electron microscopy · 1 distinct chain · 4% helix, 34% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ACapsid proteinprotein5184% helix, 34% strandQ8JQG0

Pockets

9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13420.590.7738empty
21240.530.8122empty
31010.440.7821empty
41290.430.7629empty
5980.410.7718empty

Compared structures

  • 7JOT · Adeno-associated virus strain AAV7 capsid icosahedral structure · the same entry in another collection · chain A against A, TM-score 1.00

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