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Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2413A in complex with HIV-1 GP120 core

Analyse Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7JKT
Type
protein
Length
781 residues
Chains
3
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Ligands
NAG, SO4

Structure

x-ray diffraction · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
G—protein344——
H—protein225——
L—protein212——

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 9 copies · chains G, H, L
  • SO4 · Sulfate ion · ion · 2 copies · chains H
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains G

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7JKT · Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2413a in… · the same entry in another collection · chain G against G, TM-score 1.00

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