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Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2411A in complex with HIV-1 GP120 core

Analyse Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
7JKS
Type
protein
Length
769 residues
Chains
3
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Ligands
NAG, BMA

Structure

x-ray diffraction · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
G—protein338——
H—protein224——
L—protein207——

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 9 copies · chains G, L, H
  • BMA · beta-D-mannopyranose · sugar · chains L

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7JKS · Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2411a in… · the same entry in another collection · chain G against G, TM-score 1.00

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