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Structure of ACRIF13

Analyse Structure of ACRIF13 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7FI4
Type: protein
Length: 934 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ACRIF13
UniProt: A0A3A9QXE8
Pockets: 15 · best druggability 0.75

Structure

x-ray diffraction · 4 distinct chains · 26% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, C, D, F, G	ACRIF13	protein	118	25% helix, 29% strand	A0A3A9QXE8
B	ACRIF13	protein	115	26% helix, 26% strand	A0A3A9QXE8
E	ACRIF13	protein	112	26% helix, 29% strand	A0A3A9QXE8
H	ACRIF13	protein	117	26% helix, 26% strand	A0A3A9QXE8

Pockets

15 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	268	0.75	0.89	31	empty
2	295	0.75	0.88	31	empty
3	394	0.75	0.85	54	empty
4	217	0.72	0.88	30	empty
5	253	0.61	0.80	43	empty

Interfaces

9 interfaces between chains.

B–C · 651 Å² buried · 12 hydrogen bonds · protein-protein
B–G · 640 Å² buried · 9 hydrogen bonds · protein-protein
A–D · 626 Å² buried · 10 hydrogen bonds · protein-protein
C–D · 610 Å² buried · 8 hydrogen bonds · protein-protein
A–E · 592 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

7FI4 · Structure of AcrIF13 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A3A9QXE8
Elsewhere: RCSB PDB 7FI4 · PDBe 7FI4 · UniProt A0A3A9QXE8

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