Research workbench
Diarylpentanoid-producing polyketide synthase (N199F mutant)
Analyse Diarylpentanoid-producing polyketide synthase (N199F mutant) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7FFG
- Type
- protein
- Length
- 770 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type III polyketide synthase
- UniProt
- A0A385MEG6
- Pockets
- 4 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Type III polyketide synthase | protein | 385 | 38% helix, 23% strand | A0A385MEG6 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 273 | 0.74 | 0.87 | 40 | empty |
| 2 | 626 | 0.72 | 0.79 | 53 | empty |
| 3 | 277 | 0.70 | 0.84 | 38 | empty |
| 4 | 267 | 0.48 | 0.73 | 31 | empty |
Interfaces
1 interface between chains.
- A–B · 385 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 7FFG · Diarylpentanoid-producing polyketide synthase (N199F mutant) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A385MEG6
- Elsewhere: RCSB PDB 7FFG · PDBe 7FFG · UniProt A0A385MEG6
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