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Crystal structure of human dj-1

Analyse Crystal structure of human dj-1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1P5F
Type: protein
Length: 186 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA-binding protein regulatory subunit
UniProt: Q99497
Pockets: 1 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA-binding protein regulatory subunit	protein	186	43% helix, 21% strand	Q99497

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.39	0.81	12	empty

Compared structures

1P5F · Crystal Structure of Human DJ-1 · the same entry in another collection · chain A against A, TM-score 1.00
Q99497 · AlphaFold monomer V2.0 prediction for parkinson disease protein 7 (Q99497) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99497
Elsewhere: RCSB PDB 1P5F · PDBe 1P5F · UniProt Q99497

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