Research workbench

Crystal structure of a mutant of acid phosphatase from pseudomonas aeruginosa (Q57H/W58P/D135R)

Analyse Crystal structure of a mutant of acid phosphatase from pseudomonas aeruginosa… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7F18
Type: protein
Length: 635 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Acid phosphatase
EC: 3.1.3.2
UniProt: A0A0D6FFE3
Pockets: 8 · best druggability 0.63

Structure

x-ray diffraction · 2 distinct chains · 61% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Acid phosphatase (EC 3.1.3.2)	protein	212	62% helix, 0% strand	A0A0D6FFE3
C	Acid phosphatase (EC 3.1.3.2)	protein	211	59% helix, 0% strand	A0A0D6FFE3

Pockets

8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	454	0.63	0.77	51	empty
2	385	0.59	0.76	37	empty
3	334	0.59	0.77	40	empty
4	285	0.57	0.77	37	empty
5	344	0.56	0.75	46	empty

Interfaces

2 interfaces between chains.

B–C · 1015 Å² buried · 4 hydrogen bonds · protein-protein
A–B · 468 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

7F18 · Crystal Structure of a mutant of acid phosphatase from Pseudomonas aeruginosa… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0D6FFE3
Elsewhere: RCSB PDB 7F18 · PDBe 7F18 · UniProt A0A0D6FFE3

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.