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NMR solution structure of the 1:1 complex of a quadruplex-duplex hybrid MYT1L and a PLATINUM(II) ligand L1PT(DIEN)

Analyse NMR solution structure of the 1:1 complex of a quadruplex-duplex hybrid MYT1L… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7EL7
Type: DNA
Length: 29 nucleotides
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: G-quadruplex DNA MYT1L
Ligands: J70
Pockets: 1 · best druggability 0.24

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	G-quadruplex DNA MYT1L	dna	29	—	—

Ligands and binding sites

J70 · Pt(diethylenetriamine)(2-(pyridin-4-ylmethyl) benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone) · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.24	0.73	7	J70

Compared structures

7EL7 · NMR solution structure of the 1:1 complex of a quadruplex-duplex hybrid MYT1L and a… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 7EL7 · PDBe 7EL7

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