Research workbench
Crystal structure of the candida glabrata glycogen debranching enzyme (W470A E564Q) in complex with maltononaose
Analyse Crystal structure of the candida glabrata glycogen debranching enzyme (W470A… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7EKX
- Type
- protein
- Length
- 3,052 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 4-alpha-glucanotransferase
- EC
- 2.4.1.25, 3.2.1.33
- UniProt
- Q6FSK0
- Ligands
- GLC
- Pockets
- 20 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 4-alpha-glucanotransferase (EC 2.4.1.25, 3.2.1.33) | protein | 1526 | 35% helix, 16% strand | Q6FSK0 |
Ligands and binding sites
- GLC · alpha-D-glucopyranose · sugar · 17 copies · chains B, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 18 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 809 | 0.84 | 0.86 | 82 | empty |
| 2 | 1043 | 0.83 | 0.84 | 96 | empty |
| 3 | 63 | 0.74 | 0.99 | 28 | empty |
| 4 | 544 | 0.72 | 0.81 | 60 | empty |
| 5 | 580 | 0.72 | 0.80 | 72 | empty |
Interfaces
1 interface between chains.
- A–B · 215 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 7EKX · Crystal Structure of the Candida Glabrata Glycogen Debranching Enzyme (W470A E564Q) in… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6FSK0
- Elsewhere: RCSB PDB 7EKX · PDBe 7EKX · UniProt Q6FSK0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.