Research workbench
Structure of rift valley fever virus RNA-dependent RNA polymerase
Analyse Structure of rift valley fever virus RNA-dependent RNA polymerase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7EEI
- Type
- protein
- Length
- 1,400 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Replicase
- EC
- 2.7.7.48
- UniProt
- A2SZS3
- Pockets
- 20 · best druggability 0.83
Structure
electron microscopy · 1 distinct chain · 45% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Replicase (EC 2.7.7.48) | protein | 1400 | 45% helix, 7% strand | A2SZS3 |
Pockets
20 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1028 | 0.83 | 0.84 | 140 | empty |
| 2 | 1049 | 0.81 | 0.82 | 128 | empty |
| 3 | 878 | 0.80 | 0.82 | 87 | empty |
| 4 | 52 | 0.70 | 0.98 | 18 | empty |
| 5 | 71 | 0.69 | 0.95 | 23 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7EEI · Structure of Rift Valley fever virus RNA-dependent RNA polymerase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A2SZS3
- Elsewhere: RCSB PDB 7EEI · PDBe 7EEI · UniProt A2SZS3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.