Research workbench
H102A mutant of IRG1 from bacillus
Analyse H102A mutant of IRG1 from bacillus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7E9D
- Type
- protein
- Length
- 886 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- IRG1
- Pockets
- 10 · best druggability 0.86
Structure
x-ray diffraction · 1 distinct chain · 54% helix, 8% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | IRG1 | protein | 443 | 54% helix, 8% strand | — |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 281 | 0.86 | 0.97 | 45 | empty |
| 2 | 517 | 0.72 | 0.81 | 71 | empty |
| 3 | 337 | 0.68 | 0.82 | 39 | empty |
| 4 | 94 | 0.49 | 0.82 | 18 | empty |
| 5 | 109 | 0.43 | 0.77 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 2201 Ų buried · 30 hydrogen bonds · protein-protein
Compared structures
- 7E9D · H102A mutant of IRG1 from bacillus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7E9D · PDBe 7E9D
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.