Oxy-deoxy intermediate of 400 kda giant hemoglobin at 13% oxygen saturation

Structure

x-ray diffraction · 4 distinct chains.

Ligands and binding sites

• HEM · Protoporphyrin IX containing Fe · ligand · 4 copies · chains A, D, B, C
• OXY · Oxygen molecule · ion · 4 copies · chains A, B, C, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 7E99 · Oxy-deoxy intermediate of 400 kDa giant hemoglobin at 13% oxygen saturation · the same entry in another collection · chain A against A, TM-score 1.00
• Q7M413 · AlphaFold monomer V2.0 prediction for extracellular giant hemoglobin major globin subunit… · a predicted model of the same protein · chain B against A, TM-score 0.98
• Q7M418 · AlphaFold monomer V2.0 prediction for extracellular giant hemoglobin major globin subunit… · a predicted model of the same protein · chain C against A, TM-score 0.98
• Q7M419 · AlphaFold monomer V2.0 prediction for extracellular giant hemoglobin major globin subunit… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q7M419
• Every structure of UniProt Q7M413
• Every structure of UniProt Q7M418
• Every structure of UniProt B1Q3G1
• Elsewhere: RCSB PDB 7E99 · PDBe 7E99 · UniProt Q7M419 · UniProt Q7M413 · UniProt Q7M418 · UniProt B1Q3G1