Research workbench
Crystal structure of N1051A mutant of formylglycinamidine synthetase
Analyse Crystal structure of N1051A mutant of formylglycinamidine synthetase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DW7
- Type
- protein
- Length
- 1,290 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phosphoribosylformylglycinamidine synthase
- EC
- 6.3.5.3
- UniProt
- A0A0D6F9Y3
- Ligands
- ADP, MG, SO4
- Pockets
- 10 · best druggability 0.86
Structure
x-ray diffraction · 1 distinct chain · 35% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phosphoribosylformylglycinamidine synthase (EC 6.3.5.3) | protein | 1290 | 35% helix, 27% strand | A0A0D6F9Y3 |
Ligands and binding sites
- ADP · Adenosine-5'-diphosphate · ligand · chains A
- MG · Magnesium ion · metal · 3 copies · chains A
- SO4 · Sulfate ion · ion · 19 copies · chains A
- GOL · Glycerol · additive · 40 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
10 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 297 | 0.86 | 0.97 | 48 | ADP, MG |
| 2 | 992 | 0.83 | 0.84 | 94 | GOL, SO4 |
| 3 | 996 | 0.80 | 0.81 | 83 | GOL, SO4 |
| 4 | 263 | 0.79 | 0.92 | 38 | GOL |
| 5 | 103 | 0.76 | 0.97 | 32 | GOL |
Compared structures
- 7DW7 · Crystal Structure of N1051A mutant of Formylglycinamidine Synthetase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0D6F9Y3
- Elsewhere: RCSB PDB 7DW7 · PDBe 7DW7 · UniProt A0A0D6F9Y3
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