Research workbench
Methods used in the structure determination of foot and mouth disease virus
Analyse Methods used in the structure determination of foot and mouth disease virus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1BBT
- Type
- protein
- Length
- 662 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Foot-and-mouth disease virus (subunit VP1); Foot-and-mouth disease virus (subunit VP2)…
- UniProt
- Q84771, O90754
- Pockets
- 6 · best druggability 0.78
Structure
x-ray diffraction · 4 distinct chains · 12% helix, 34% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 1 | Foot-and-mouth disease virus (subunit VP1) | protein | 186 | 15% helix, 30% strand | Q84771 |
| 2 | Foot-and-mouth disease virus (subunit VP2) | protein | 210 | 10% helix, 45% strand | Q84771 |
| 3 | Foot-and-mouth disease virus (subunit VP3) | protein | 220 | 9% helix, 33% strand | Q84771 |
| 4 | Foot-and-mouth disease virus (subunit VP4) | protein | 46 | 26% helix, 2% strand | O90754 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1091 | 0.78 | 0.79 | 107 | empty |
| 2 | 602 | 0.71 | 0.79 | 63 | empty |
| 3 | 160 | 0.47 | 0.76 | 25 | empty |
| 4 | 89 | 0.36 | 0.76 | 19 | empty |
| 5 | 75 | 0.36 | 0.77 | 17 | empty |
Interfaces
6 interfaces between chains.
- 1–2 · 1343 Ų buried · 20 hydrogen bonds · protein-protein
- 1–3 · 989 Ų buried · 17 hydrogen bonds · protein-protein
- 2–3 · 916 Ų buried · 11 hydrogen bonds · protein-protein
- 1–4 · 779 Ų buried · 15 hydrogen bonds · protein-protein
- 2–4 · 249 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 1BBT · Methods used in the structure determination of foot and mouth disease virus · the same entry in another collection · chain 2 against 2, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q84771
- Every structure of UniProt O90754
- Elsewhere: RCSB PDB 1BBT · PDBe 1BBT · UniProt Q84771 · UniProt O90754
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