Research workbench
Apo crystal structure of octaketide synthase from a. arborescens
Analyse Apo crystal structure of octaketide synthase from a. arborescens in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DTQ
- Type
- protein
- Length
- 1,560 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Octaketide synthase 1
- EC
- 2.3.1.-
- UniProt
- Q3L7F5
- Pockets
- 11 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Octaketide synthase 1 (EC 2.3.1.-) | protein | 390 | 44% helix, 24% strand | Q3L7F5 |
Pockets
11 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 578 | 0.77 | 0.84 | 62 | empty |
| 2 | 350 | 0.76 | 0.86 | 59 | empty |
| 3 | 344 | 0.75 | 0.86 | 50 | empty |
| 4 | 303 | 0.74 | 0.86 | 53 | empty |
| 5 | 291 | 0.56 | 0.76 | 35 | empty |
Interfaces
3 interfaces between chains.
- A–B · 3132 Ų buried · 79 hydrogen bonds · protein-protein
- A–C · 363 Ų buried · 4 hydrogen bonds · protein-protein
- B–D · 178 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3L7F5
- Elsewhere: RCSB PDB 7DTQ · PDBe 7DTQ · UniProt Q3L7F5
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