Research workbench
Crystal structure of the RECA1 domain of RNA helicase cgh-1 in C. elegans
Analyse Crystal structure of the RECA1 domain of RNA helicase cgh-1 in C. elegans in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DTK
- Type
- protein
- Length
- 407 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ATP-dependent RNA helicase cgh-1
- EC
- 3.6.4.13
- UniProt
- Q95YF3
- Pockets
- 2 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | ATP-dependent RNA helicase cgh-1 (EC 3.6.4.13) | protein | 204 | 45% helix, 15% strand | Q95YF3 |
| A | ATP-dependent RNA helicase cgh-1 (EC 3.6.4.13) | protein | 203 | 45% helix, 15% strand | Q95YF3 |
Ligands and binding sites
- GOL · Glycerol · additive · 4 copies · chains B, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 628 | 0.66 | 0.76 | 66 | GOL |
| 2 | 58 | 0.30 | 0.75 | 16 | empty |
Interfaces
1 interface between chains.
- B–A · 345 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7DTK · Crystal structure of the RecA1 domain of RNA helicase CGH-1 in C. elegans · the same entry in another collection · chain B against B, TM-score 1.00
- Q95YF3 · AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase cgh-1 (Q95YF3) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q95YF3
- Elsewhere: RCSB PDB 7DTK · PDBe 7DTK · UniProt Q95YF3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.