Research workbench
Crystal structure of lamin B1 ig-like domain from human
Analyse Crystal structure of lamin B1 ig-like domain from human in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DTG
- Type
- protein
- Length
- 708 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Lamin-B1
- UniProt
- P20700
- Pockets
- 6 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 3% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, F, E | Lamin-B1 | protein | 118 | 3% helix, 50% strand | P20700 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 253 | 0.70 | 0.86 | 52 | empty |
| 2 | 160 | 0.69 | 0.89 | 45 | empty |
| 3 | 149 | 0.63 | 0.86 | 40 | empty |
| 4 | 252 | 0.50 | 0.74 | 35 | empty |
| 5 | 204 | 0.44 | 0.73 | 32 | empty |
Interfaces
6 interfaces between chains.
- C–D · 562 Ų buried · 7 hydrogen bonds · protein-protein
- A–E · 556 Ų buried · 6 hydrogen bonds · protein-protein
- B–F · 540 Ų buried · 9 hydrogen bonds · protein-protein
- B–C · 480 Ų buried · 7 hydrogen bonds · protein-protein
- A–B · 309 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P20700
- Elsewhere: RCSB PDB 7DTG · PDBe 7DTG · UniProt P20700
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