Research workbench
Crystal structure of AMUC_1102 from akkermansia muciniphila
Analyse Crystal structure of AMUC_1102 from akkermansia muciniphila in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DSZ
- Type
- protein
- Length
- 568 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- AMUC_1102
- UniProt
- B2UR43
- Ligands
- CL
- Pockets
- 8 · best druggability 0.85
Structure
x-ray diffraction · 3 distinct chains · 11% helix, 45% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | AMUC_1102 | protein | 186 | 11% helix, 46% strand | B2UR43 |
| B | AMUC_1102 | protein | 190 | 11% helix, 45% strand | B2UR43 |
| C | AMUC_1102 | protein | 192 | 10% helix, 45% strand | B2UR43 |
Ligands and binding sites
- CL · Chloride ion · ion · 5 copies · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1070 | 0.85 | 0.86 | 133 | empty |
| 2 | 52 | 0.66 | 0.95 | 15 | empty |
| 3 | 94 | 0.51 | 0.83 | 16 | empty |
| 4 | 149 | 0.49 | 0.78 | 22 | empty |
| 5 | 140 | 0.44 | 0.76 | 21 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1517 Ų buried · 23 hydrogen bonds · protein-protein
- B–C · 1488 Ų buried · 23 hydrogen bonds · protein-protein
- A–C · 1294 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 7DSZ · Crystal structure of Amuc_1102 from Akkermansia muciniphila · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2UR43
- Elsewhere: RCSB PDB 7DSZ · PDBe 7DSZ · UniProt B2UR43
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.