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Crystal structure of sulfurisphaera tokodaii O6-methylguanine methyltransferase Y91F/C120S variant in complex with O6- methyldeoxyguanosine

Analyse Crystal structure of sulfurisphaera tokodaii O6-methylguanine methyltransferase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7DQQ
Type: protein
Length: 149 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Methylated-DNA--protein-cysteine methyltransferase
EC: 2.1.1.63
UniProt: Q973C7
Ligands: J03

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63)	protein	149	40% helix, 19% strand	Q973C7

Ligands and binding sites

J03 · (2~{R},3~{S},5~{R})-5-(2-azanyl-6-methoxy-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

7DQQ · Crystal structure of Sulfurisphaera tokodaii O6-methylguanine methyltransferase… · the same entry in another collection · chain A against A, TM-score 1.00
Q973C7 · AlphaFold monomer V2.0 prediction for methylated-DNA--protein- cysteine methyltransferase… · a predicted model of the same protein · chain A against A, TM-score 0.99

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q973C7
Elsewhere: RCSB PDB 7DQQ · PDBe 7DQQ · UniProt Q973C7

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