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Crystal structure of PDZD7 hhd domain
Analyse Crystal structure of PDZD7 hhd domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DE7
- Type
- protein
- Length
- 190 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PDZ domain-containing protein 7
- UniProt
- E9Q9W7
- Ligands
- 2Q5
- Pockets
- 1 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 85% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PDZ domain-containing protein 7 | protein | 97 | 85% helix, 0% strand | E9Q9W7 |
| B | PDZ domain-containing protein 7 | protein | 93 | 85% helix, 0% strand | E9Q9W7 |
Ligands and binding sites
- 2Q5 · (2R)-2-{[(2R)-2-{[(2S)-2-{[(2R)-2-hydroxypropyl]oxy}propyl]oxy}propyl]oxy}propan-1-ol · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 360 | 0.74 | 0.84 | 31 | 2Q5 |
Interfaces
1 interface between chains.
- A–B · 1024 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E9Q9W7
- Elsewhere: RCSB PDB 7DE7 · PDBe 7DE7 · UniProt E9Q9W7
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