Research workbench
Cryo-EM structure of the deah-box helicase PRP2
Analyse Cryo-EM structure of the deah-box helicase PRP2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DCQ
- Type
- protein
- Length
- 653 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- PRP2 isoform 1
- UniProt
- A0A6A5Q5S8
- Pockets
- 11 · best druggability 0.77
Structure
electron microscopy · 1 distinct chain · 43% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| x | PRP2 isoform 1 | protein | 653 | 43% helix, 18% strand | A0A6A5Q5S8 |
Pockets
11 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 416 | 0.77 | 0.86 | 63 | empty |
| 2 | 221 | 0.72 | 0.88 | 30 | empty |
| 3 | 101 | 0.59 | 0.86 | 23 | empty |
| 4 | 51 | 0.57 | 0.91 | 19 | empty |
| 5 | 82 | 0.53 | 0.85 | 19 | empty |
Compared structures
- 7DCQ · cryo-EM structure of the DEAH-box helicase Prp2 · the same entry in another collection · chain x against x, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A6A5Q5S8
- Elsewhere: RCSB PDB 7DCQ · PDBe 7DCQ · UniProt A0A6A5Q5S8
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