Research workbench
Crystal structure of human ldhb in complex with NADH, oxamate, and axko-0046
Analyse Crystal structure of human ldhb in complex with NADH, oxamate, and axko-0046 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DBJ
- Type
- protein
- Length
- 1,332 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P07195
- Ligands
- NAI, OXM, H1U
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | — | protein | 333 | — | P07195 |
Ligands and binding sites
- NAI · 1,4-dihydronicotinamide adenine dinucleotide · ligand · 4 copies · chains A, B, C, D
- OXM · Oxamic acid · ligand · 4 copies · chains A, B, C, D
- H1U · N-[[3-[2-[(phenylmethyl)amino]ethyl]-1H-indol-2-yl]methyl]cycloheptanamine · ligand · 2 copies · chains A, C, B, D
- EDO · 1,2-ethanediol · additive · 7 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7DBJ · Crystal structure of human LDHB in complex with NADH, oxamate, and AXKO-0046 · the same entry in another collection · chain A against A, TM-score 1.00
- P07195 · AlphaFold monomer V2.0 prediction for L-lactate dehydrogenase B chain (P07195) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07195
- Elsewhere: RCSB PDB 7DBJ · PDBe 7DBJ · UniProt P07195
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