Research workbench
Coupling of folding and binding in the ptb domain of the signaling protein shc
Analyse Coupling of folding and binding in the ptb domain of the signaling protein shc in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1OY2
- Type
- protein
- Length
- 191 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Shc transforming protein
- UniProt
- P29353
- Pockets
- 3 · best druggability 0.69
Structure
solution nmr · 1 distinct chain · 14% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Shc transforming protein | protein | 191 | 14% helix, 20% strand | P29353 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 334 | 0.69 | 0.82 | 46 | empty |
| 2 | 121 | 0.63 | 0.87 | 26 | empty |
| 3 | 57 | 0.30 | 0.76 | 14 | empty |
Compared structures
- 1OY2 · Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc · the same entry in another collection · chain A against A, TM-score 1.00
- P29353 · AlphaFold monomer V2.0 prediction for shc-transforming protein 1 (P29353) · a predicted model of the same protein · chain A against A, TM-score 0.66
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P29353
- Elsewhere: RCSB PDB 1OY2 · PDBe 1OY2 · UniProt P29353
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