Research workbench
Atomic structure of a cytochrome C' with an unusual ligand-controlled dimer dissociation at 1.8 ångströms resolution
Analyse Atomic structure of a cytochrome C' with an unusual ligand-controlled dimer… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1BBH
- Type
- protein
- Length
- 262 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cytochrome C'
- UniProt
- P00154
- Ligands
- HEC
- Pockets
- 3 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 74% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Cytochrome C' | protein | 131 | 74% helix, 3% strand | P00154 |
Ligands and binding sites
- HEC · Heme C · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 333 | 0.69 | 0.82 | 34 | HEC |
| 2 | 300 | 0.69 | 0.83 | 32 | HEC |
| 3 | 72 | 0.29 | 0.72 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 771 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 cofactor (heme c attachment).
Compared structures
- 1BBH · Atomic structure of a cytochrome C' with an unusual ligand-controlled dimer dissociation… · the same entry in another collection · chain A against A, TM-score 1.00
- P00154 · AlphaFold monomer V2.0 prediction for cytochrome C' (P00154) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00154
- Elsewhere: RCSB PDB 1BBH · PDBe 1BBH · UniProt P00154
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.