Research workbench
Hexachlorobenzene monooxygenase (HCBA1) from nocardioides sp. strain PD653 complexed with FMN
Analyse Hexachlorobenzene monooxygenase (HCBA1) from nocardioides sp. strain PD653… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7CZA
- Type
- protein
- Length
- 838 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hexachlorobenzene oxidative dehalogenase
- UniProt
- A0A1V1W347
- Ligands
- FMN
- Pockets
- 9 · best druggability 0.77
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Hexachlorobenzene oxidative dehalogenase | protein | 419 | 41% helix, 16% strand | A0A1V1W347 |
Ligands and binding sites
- FMN · Flavin mononucleotide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 761 | 0.77 | 0.81 | 55 | FMN |
| 2 | 777 | 0.75 | 0.79 | 51 | FMN |
| 3 | 262 | 0.63 | 0.81 | 27 | empty |
| 4 | 70 | 0.53 | 0.86 | 16 | empty |
| 5 | 143 | 0.48 | 0.78 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 3002 Ų buried · 42 hydrogen bonds · protein-protein
Compared structures
- 7CZA · Hexachlorobenzene monooxygenase (HcbA1) from Nocardioides sp. strain PD653 complexed with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1V1W347
- Elsewhere: RCSB PDB 7CZA · PDBe 7CZA · UniProt A0A1V1W347
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