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Structure of the 328-692 fragment of flha (E351A/D356A)

Analyse Structure of the 328-692 fragment of flha (E351A/D356A) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7CTN
Type: protein
Length: 679 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Flagellar biosynthesis protein flha
UniProt: P40729
Pockets: 6 · best druggability 0.76

Structure

x-ray diffraction · 2 distinct chains · 46% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Flagellar biosynthesis protein flha	protein	345	47% helix, 17% strand	P40729
B	Flagellar biosynthesis protein flha	protein	334	45% helix, 19% strand	P40729

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	939	0.76	0.79	71	empty
2	383	0.58	0.75	45	empty
3	124	0.42	0.76	18	empty
4	81	0.33	0.74	25	empty
5	77	0.32	0.74	14	empty

Interfaces

1 interface between chains.

A–B · 481 Å² buried · 3 hydrogen bonds · protein-protein

Compared structures

7CTN · Structure of the 328-692 fragment of FlhA (E351A/D356A) · the same entry in another collection · chain A against A, TM-score 1.00
P40729 · AlphaFold monomer V2.0 prediction for flagellar biosynthesis protein flha (P40729) · a predicted model of the same protein · chain B against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P40729
Elsewhere: RCSB PDB 7CTN · PDBe 7CTN · UniProt P40729

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