Research workbench
Crystal structure and functional analysis of drosophila wind-- a pdi- related protein
Analyse Crystal structure and functional analysis of drosophila wind-- a pdi- related… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1OVN
- Type
- protein
- Length
- 455 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Windbeutel
- UniProt
- O44342
- Ligands
- CS
- Pockets
- 5 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 49% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Windbeutel | protein | 229 | 50% helix, 11% strand | O44342 |
| B | Windbeutel | protein | 226 | 48% helix, 12% strand | O44342 |
Ligands and binding sites
- CS · Cesium ion · metal · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 301 | 0.53 | 0.75 | 46 | empty |
| 2 | 145 | 0.45 | 0.77 | 30 | empty |
| 3 | 81 | 0.37 | 0.76 | 17 | empty |
| 4 | 60 | 0.26 | 0.72 | 13 | empty |
| 5 | 50 | 0.26 | 0.73 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 770 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 1OVN · Crystal Structure and Functional Analysis of Drosophila Wind-- a PDI-Related Protein · the same entry in another collection · chain A against A, TM-score 1.00
- O44342 · AlphaFold monomer V2.0 prediction for protein windbeutel (O44342) · a predicted model of the same protein · chain B against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O44342
- Elsewhere: RCSB PDB 1OVN · PDBe 1OVN · UniProt O44342
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