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Crystal structure of the starter condensation domain of rhizomide synthetase rzma mutant H140V/R148A in a "product-released" conformation
Analyse Crystal structure of the starter condensation domain of rhizomide synthetase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7C1U
- Type
- protein
- Length
- 433 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Non-ribosomal peptide synthetase modules
- EC
- 6.3.2.-
- UniProt
- E5ATN9
- Pockets
- 5 · best druggability 0.85
Structure
x-ray diffraction · 1 distinct chain · 39% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Non-ribosomal peptide synthetase modules (EC 6.3.2.-) | protein | 433 | 39% helix, 21% strand | E5ATN9 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1013 | 0.85 | 0.85 | 92 | empty |
| 2 | 114 | 0.62 | 0.87 | 30 | empty |
| 3 | 79 | 0.55 | 0.86 | 20 | empty |
| 4 | 57 | 0.35 | 0.78 | 13 | empty |
| 5 | 53 | 0.34 | 0.78 | 15 | empty |
Compared structures
- 7C1U · Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E5ATN9
- Elsewhere: RCSB PDB 7C1U · PDBe 7C1U · UniProt E5ATN9
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