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Crystal structure of the ferm domain of FRMPD4

Analyse Crystal structure of the ferm domain of FRMPD4 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7BYJ
Type: protein
Length: 331 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ferm and PDZ domain-containing protein 4
UniProt: Q14CM0
Pockets: 5 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ferm and PDZ domain-containing protein 4	protein	331	40% helix, 26% strand	Q14CM0

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	280	0.66	0.82	42	empty
2	110	0.55	0.84	21	empty
3	129	0.47	0.77	15	empty
4	115	0.36	0.73	19	empty
5	96	0.36	0.74	18	empty

Compared structures

7BYJ · Crystal structure of the FERM domain of FRMPD4 · the same entry in another collection · chain A against A, TM-score 1.00
Q14CM0 · AlphaFold monomer V2.0 prediction for ferm and PDZ domain-containing protein 4 (Q14CM0) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q14CM0
Elsewhere: RCSB PDB 7BYJ · PDBe 7BYJ · UniProt Q14CM0

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