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Crystal structure of PCNA from pathogenic yeast candida albicans

Analyse Crystal structure of PCNA from pathogenic yeast candida albicans in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7BUP
Type: protein
Length: 741 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Proliferating cell nuclear antigen
UniProt: Q5AMN0
Pockets: 1 · best druggability 0.31

Structure

x-ray diffraction · 3 distinct chains · 19% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Proliferating cell nuclear antigen	protein	240	20% helix, 45% strand	Q5AMN0
B	Proliferating cell nuclear antigen	protein	255	19% helix, 45% strand	Q5AMN0
C	Proliferating cell nuclear antigen	protein	246	20% helix, 48% strand	Q5AMN0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.31	0.76	15	empty

Interfaces

3 interfaces between chains.

B–C · 758 Å² buried · 14 hydrogen bonds · protein-protein
A–C · 732 Å² buried · 12 hydrogen bonds · protein-protein
A–B · 725 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

7BUP · Crystal structure of PCNA from pathogenic yeast Candida albicans · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5AMN0
Elsewhere: RCSB PDB 7BUP · PDBe 7BUP · UniProt Q5AMN0

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