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Microed structure of the MYD88 tir domain higher-order assembly

Analyse Microed structure of the MYD88 tir domain higher-order assembly in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7BEQ
Type: protein
Length: 138 residues
Chains: 1
Method: electron crystallography
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myeloid differentiation primary response protein MYD88
UniProt: Q99836
Pockets: 2 · best druggability 0.43

Structure

electron crystallography · 1 distinct chain · 42% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Myeloid differentiation primary response protein MYD88	protein	138	42% helix, 14% strand	Q99836

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	96	0.43	0.78	18	empty
2	75	0.35	0.76	19	empty

Compared structures

7BEQ · MicroED structure of the MyD88 TIR domain higher-order assembly · the same entry in another collection · chain A against A, TM-score 1.00
Q99836 · AlphaFold monomer V2.0 prediction for myeloid differentiation primary response protein… · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q99836
Elsewhere: RCSB PDB 7BEQ · PDBe 7BEQ · UniProt Q99836

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