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Human BCL6 btb-domain in complex with GSK137

Analyse Human BCL6 btb-domain in complex with GSK137 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7BDE
Type: protein
Length: 126 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Isoform 2 of B-cell lymphoma 6 protein
UniProt: P41182
Ligands: TEQ

Structure

x-ray diffraction · 1 distinct chain · 54% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Isoform 2 of B-cell lymphoma 6 protein	protein	126	54% helix, 10% strand	P41182

Ligands and binding sites

TEQ · 5-[(5S,7R)-3-fluoranyl-7-(2-methylpyridin-3-yl)-4,5,6, 7-tetrahydropyrazolo[1,5-a]pyrimidin-5-yl]quinolin-2-amine · ligand · chains A
GOL · Glycerol · additive · chains A
DMS · Dimethyl sulfoxide · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7BDE · Human BCL6 btb-domain in complex with GSK137 · the same entry in another collection · chain A against A, TM-score 1.00
P41182 · AlphaFold monomer V2.0 prediction for B-cell lymphoma 6 protein (P41182) · a predicted model of the same protein · chain A against A, TM-score 0.31

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P41182
Elsewhere: RCSB PDB 7BDE · PDBe 7BDE · UniProt P41182

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