Research workbench
Ornithine transcarbamoylase from pseudomonas aeruginosa
Analyse Ornithine transcarbamoylase from pseudomonas aeruginosa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1ORT
- Type
- protein
- Length
- 4,020 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ornithine transcarbamoylase
- EC
- 2.1.3.3
- UniProt
- P08308
- Pockets
- 20 · best druggability 0.91
Structure
x-ray diffraction · 1 distinct chain · 46% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J, K, L | Ornithine transcarbamoylase (EC 2.1.3.3) | protein | 335 | 46% helix, 13% strand | P08308 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 964 | 0.91 | 0.93 | 111 | empty |
| 2 | 1114 | 0.90 | 0.92 | 112 | empty |
| 3 | 741 | 0.89 | 0.93 | 89 | empty |
| 4 | 616 | 0.88 | 0.93 | 74 | empty |
| 5 | 871 | 0.85 | 0.88 | 132 | empty |
Interfaces
30 interfaces between chains.
- C–D · 1213 Ų buried · 21 hydrogen bonds · protein-protein
- F–J · 1213 Ų buried · 21 hydrogen bonds · protein-protein
- A–L · 1209 Ų buried · 21 hydrogen bonds · protein-protein
- G–I · 1209 Ų buried · 21 hydrogen bonds · protein-protein
- B–F · 1208 Ų buried · 21 hydrogen bonds · protein-protein
Compared structures
- 1ORT · Ornithine transcarbamoylase from pseudomonas aeruginosa · the same entry in another collection · chain H against H, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P08308
- Elsewhere: RCSB PDB 1ORT · PDBe 1ORT · UniProt P08308
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