Research workbench

D319A mutant of the pilb minor pilin from streptococcus sanguinis

Analyse D319A mutant of the pilb minor pilin from streptococcus sanguinis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7BA2
Type: protein
Length: 839 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Type IV pilus biogenesis protein pilb
UniProt: A0A0B7GP99
Pockets: 5 · best druggability 0.69

Structure

x-ray diffraction · 2 distinct chains · 30% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Type IV pilus biogenesis protein pilb	protein	419	30% helix, 28% strand	A0A0B7GP99
B	Type IV pilus biogenesis protein pilb	protein	420	30% helix, 26% strand	A0A0B7GP99

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	418	0.69	0.81	48	empty
2	58	0.33	0.77	13	empty
3	62	0.33	0.76	11	empty
4	54	0.29	0.75	14	empty
5	55	0.27	0.74	16	empty

Interfaces

1 interface between chains.

A–B · 744 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

7BA2 · D319A mutant of the PilB minor pilin from Streptococcus sanguinis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0B7GP99
Elsewhere: RCSB PDB 7BA2 · PDBe 7BA2 · UniProt A0A0B7GP99

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