Research workbench
Nhl domain of human TRIM2
Analyse Nhl domain of human TRIM2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7B96
- Type
- protein
- Length
- 560 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Isoform 2 of tripartite motif-containing protein 2
- EC
- 2.3.2.27
- UniProt
- Q9C040
- Pockets
- 4 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 1% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Isoform 2 of tripartite motif-containing protein 2 (EC 2.3.2.27) | protein | 280 | 1% helix, 49% strand | Q9C040 |
Pockets
4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 459 | 0.70 | 0.81 | 39 | empty |
| 2 | 526 | 0.67 | 0.78 | 58 | empty |
| 3 | 360 | 0.67 | 0.80 | 39 | empty |
| 4 | 340 | 0.66 | 0.80 | 34 | empty |
Interfaces
1 interface between chains.
- A–B · 650 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9C040
- Elsewhere: RCSB PDB 7B96 · PDBe 7B96 · UniProt Q9C040
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.