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Crystal structure of chlamydomonas reinhardtii chloroplastic sedoheptulose-1,7-bisphosphatase
Analyse Crystal structure of chlamydomonas reinhardtii chloroplastic… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7B2O
- Type
- protein
- Length
- 1,859 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fbpase domain-containing protein
- EC
- 3.1.3.37
- UniProt
- A0A2K3DY10
- Pockets
- 20 · best druggability 0.75
Structure
x-ray diffraction · 5 distinct chains · 35% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fbpase domain-containing protein (EC 3.1.3.37) | protein | 311 | 34% helix, 30% strand | A0A2K3DY10 |
| B, F | Fbpase domain-containing protein (EC 3.1.3.37) | protein | 309 | 36% helix, 30% strand | A0A2K3DY10 |
| C | Fbpase domain-containing protein (EC 3.1.3.37) | protein | 309 | 35% helix, 28% strand | A0A2K3DY10 |
| D | Fbpase domain-containing protein (EC 3.1.3.37) | protein | 310 | 35% helix, 29% strand | A0A2K3DY10 |
| E | Fbpase domain-containing protein (EC 3.1.3.37) | protein | 311 | 34% helix, 26% strand | A0A2K3DY10 |
Pockets
20 pockets found on a 1 Å grid, 11 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1083 | 0.75 | 0.78 | 63 | empty |
| 2 | 179 | 0.69 | 0.87 | 25 | empty |
| 3 | 421 | 0.65 | 0.78 | 49 | empty |
| 4 | 393 | 0.63 | 0.78 | 43 | empty |
| 5 | 119 | 0.63 | 0.87 | 19 | empty |
Interfaces
7 interfaces between chains.
- B–E · 2163 Ų buried · 37 hydrogen bonds · protein-protein
- C–D · 2066 Ų buried · 34 hydrogen bonds · protein-protein
- A–F · 2048 Ų buried · 27 hydrogen bonds · protein-protein
- A–B · 884 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 359 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 7B2O · Crystal structure of Chlamydomonas reinhardtii chloroplastic… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A2K3DY10
- Elsewhere: RCSB PDB 7B2O · PDBe 7B2O · UniProt A0A2K3DY10
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