Research workbench
Crystal structure of stall-1 and bcma
Analyse Crystal structure of stall-1 and bcma in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1OQD
- Type
- protein
- Length
- 1,734 residues
- Chains
- 18
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tumor necrosis factor ligand superfamily member 13B, soluble form; Tumor necrosis factor…
- UniProt
- Q9Y275, Q02223
- Pockets
- 20 · best druggability 0.75
Structure
x-ray diffraction · 3 distinct chains · 8% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, H, I, J | Tumor necrosis factor ligand superfamily member 13B, soluble form | protein | 144 | 0% helix, 56% strand | Q9Y275 |
| K, L, M, O, P, Q, R | Tumor necrosis factor receptor superfamily member 17 | protein | 39 | 33% helix, 21% strand | Q02223 |
| N | Tumor necrosis factor receptor superfamily member 17 | protein | 21 | 19% helix, 29% strand | Q02223 |
Pockets
20 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 58 | 0.75 | 0.99 | 13 | empty |
| 2 | 139 | 0.75 | 0.93 | 20 | empty |
| 3 | 59 | 0.74 | 0.99 | 12 | empty |
| 4 | 127 | 0.74 | 0.93 | 20 | empty |
| 5 | 54 | 0.74 | 0.99 | 12 | empty |
Interfaces
38 interfaces between chains.
- E–F · 996 Ų buried · 26 hydrogen bonds · protein-protein
- G–I · 996 Ų buried · 24 hydrogen bonds · protein-protein
- D–E · 993 Ų buried · 29 hydrogen bonds · protein-protein
- D–F · 990 Ų buried · 24 hydrogen bonds · protein-protein
- H–I · 989 Ų buried · 27 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 32 disulfide (disulfide).
Compared structures
- 1OQD · Crystal structure of sTALL-1 and BCMA · the same entry in another collection · chain R against R, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y275
- Every structure of UniProt Q02223
- Elsewhere: RCSB PDB 1OQD · PDBe 1OQD · UniProt Q9Y275 · UniProt Q02223
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.