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Streptococcal high identity repeats in tandem (shirt) domain 10 from cell surface protein SGO_0707

Analyse Streptococcal high identity repeats in tandem (shirt) domain 10 from cell… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7AVK
Type: protein
Length: 166 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lpxtg cell wall surface protein
UniProt: A8AW49
Ligands: IS8
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · 2 distinct chains · 5% helix, 46% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lpxtg cell wall surface protein	protein	83	5% helix, 45% strand	A8AW49
B	Lpxtg cell wall surface protein	protein	83	5% helix, 47% strand	A8AW49

Ligands and binding sites

IS8 · isothiocyanate · ligand · 5 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	148	0.49	0.78	35	empty

Interfaces

1 interface between chains.

A–B · 486 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

7AVK · Streptococcal High Identity Repeats in Tandem (SHIRT) domain 10 from cell surface protein… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A8AW49
Elsewhere: RCSB PDB 7AVK · PDBe 7AVK · UniProt A8AW49

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