Research workbench
43S preinitiation complex from trypanosoma cruzi with the KDDX60 helicase bound with ATP
Analyse 43S preinitiation complex from trypanosoma cruzi with the KDDX60 helicase bound… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7ASK
- Type
- protein
- Length
- 1,523 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- KDDX60
- UniProt
- Q4E5Z1
- Ligands
- ADP, MG
- Pockets
- 20 · best druggability 0.81
Structure
electron microscopy · 1 distinct chain · 40% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| F | KDDX60 | protein | 1523 | 40% helix, 5% strand | Q4E5Z1 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 175 | 0.81 | 0.95 | 40 | empty |
| 2 | 754 | 0.78 | 0.82 | 77 | MG, ADP |
| 3 | 1077 | 0.77 | 0.80 | 103 | empty |
| 4 | 636 | 0.74 | 0.80 | 77 | empty |
| 5 | 509 | 0.74 | 0.82 | 61 | empty |
Compared structures
- 7ASK · 43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase bound with ATP · the same entry in another collection · chain F against F, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4E5Z1
- Elsewhere: RCSB PDB 7ASK · PDBe 7ASK · UniProt Q4E5Z1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.