Research workbench
HIV-1 gag immature lattice. GAGDELTAMASP1T8I
Analyse HIV-1 gag immature lattice. GAGDELTAMASP1T8I in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7ASH
- Type
- protein
- Length
- 4,194 residues
- Chains
- 18
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Gag protein
- UniProt
- C9DXR6
- Pockets
- 20 · best druggability 0.85
Structure
electron microscopy · 1 distinct chain · 62% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, I, N, E, J, O, F, K, P, G, L, Q, H, M, R | Gag protein | protein | 233 | 62% helix, 0% strand | C9DXR6 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 964 | 0.85 | 0.86 | 97 | empty |
| 2 | 1095 | 0.84 | 0.85 | 105 | empty |
| 3 | 1134 | 0.84 | 0.84 | 96 | empty |
| 4 | 830 | 0.83 | 0.86 | 86 | empty |
| 5 | 924 | 0.83 | 0.85 | 87 | empty |
Interfaces
36 interfaces between chains.
- E–F · 1241 Ų buried · 11 hydrogen bonds · protein-protein
- A–H · 1241 Ų buried · 6 hydrogen bonds · protein-protein
- A–D · 1236 Ų buried · 8 hydrogen bonds · protein-protein
- K–P · 1225 Ų buried · 9 hydrogen bonds · protein-protein
- D–E · 1222 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 18 disulfide (disulfide).
Compared structures
- 7ASH · HIV-1 Gag immature lattice. GagdeltaMASP1T8I · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt C9DXR6
- Elsewhere: RCSB PDB 7ASH · PDBe 7ASH · UniProt C9DXR6
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